Adobe has announced the released of CS6, which will be officially out within in 30 days. You can still buy outright, but it does seem that cloud makes more sense.
The prices can be seen on the product comparison page. Even the Master collection, which is a $549 upgrade or $2599 full seems a better deal in the cloud, as a $30 a month initial deal with a year subscription makes it much cheaper, and you already know you will get a new version every year.