Sometimes your Mac is running badly and needs some maintenance, now there are a couple of paid utilities I fall back to (mainly TechTool and Diskwarrior, but I will post more about those later) but the first I run is always the free OnyX. Onyx is a GUI or graphical user interface for various terminal utilities. It is from Titanium Software and has different versions for each version of the OS.
I always go to Maintenance and usually run everything except disk positions on desktop. It will quit all open apps and run. And the run will take a while, maybe even an hour depending on hard drive size, then will restart your machine.
I run this when Premiere is being sketchy, lots of crashes, and the system just seems to be running wrong. It isn’t a utility for Premiere, but for your system overall.